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Antioxidant therapy with vitamin C can alleviate oxidative stress and free radical damage caused by smoking

Researchers at the University of Pennsylvania measured the urine levels of a type of prostaglandin which is a stable product of lipid peroxidation and is indicative of the level of oxidative damage in smokers. The prostaglandin levels are higher in smokers and drop after stopping smoking and after vitamin C supplementation.. Neither vitamin E therapy alone or aspiring therapy reduced the prostaglandin levels.

This study provides further evidence that vitamin C exerts its protective effects via its ability to reduce free radical damage to fats.

Circulation, 1996, 94